| Home team | Harlequins |
| Away team | Sale Sharks |
| Venue | The Stoop |
| Competition | Gallagher Prem |
| Kick off time | 3 pm |
| Watch Live in the UK | TNT Sports/HBO Max |
Harlequins vs Sale Sharks Gallagher Prem Preview as the sides meet at the Stoop.
Quins have had a difficult season, sitting ninth out of 10 teams. They are eight points clear of Newcastle in last place, but are one point behind Gloucester and further behind Sale above.
Sale sit in seventh but have space on either side of the table. They are 16 points behind the Saracens and six points ahead of Gloucester below.
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Harlequins vs Sale Sharks lineups tbc
| Harlequins | Sale Sharks | ||||
| Forwards | |||||
| Hobson | 1 | McEachran | |||
| Turner | 2 | Longstaff | |||
| Jones | 3 | Opoku-Fordjour | |||
| Cunningham-South | 4 | van Rhyn | |||
| Lanchbury | 5 | Bamber | |||
| Pagadizabal | 6 | Vermeulen | |||
| Kenningham | 7 | Woodman | |||
| Dombrandt | 8 | Dugdale | |||
| Backs | |||||
| Friday | 9 | Warr | |||
| Smith | 10 | Ford | |||
| Hyde | 11 | Reed | |||
| Bradley | 12 | Ma’asi-White | |||
| Northmore | 13 | Du-Preez | |||
| Anderson | 14 | Roebuck | |||
| Benson | 15 | O’Flaherty | |||
| Replacements | |||||
| Riley | 16 | Caine | |||
| Clarke | 17 | Onasanya | |||
| Streeter | 18 | Harper | |||
| Treadwell | 19 | Andrews | |||
| Carr | 20 | Kelly | |||
| Evans | 21 | Hanson | |||
| Grant | 22 | Louw | |||
| Kerr | 23 | Davies | |||
Recent Form:
Harlequins (Home team):
| Result | Date | Competition | Opponent | Score |
| Loss | 18th April 2026 | Prem | Bath | 48-15 |
| Loss | 4th April 2026 | Champions Cup | Sale Sharks | 17-26 |
| Won | 28th March 2026 | Prem | Bristol Bears | 14-18 |
| Loss | 21st March 2026 | Prem | Gloucester | 19-26 |
| Won | 28th February 2026 | Prem Cup | Newcastle Red Bulls | 35-14 |
Harlequins have had mixed results in the Prem recently, with one win in the last three against teams around them in the table. They lost last week to a strong Bath team, conceding eight tries. Quins had competed well, bringing the score back to 25-15 shortly after halftime, but conceded four more tries in the final 30 minutes.
Sale Sharks (Away team):
| Result | Date | Competition | Opponent | Score |
| Loss | 19th April 2026 | Gallagher Prem | Saracens | 19-85 |
| Loss | 11th April 2026 | Champions Cup | Leinster | 41-13 |
| Won | 4th April 2026 | Champions Cup | Harlequins | 17-26 |
| Loss | 29th March 2026 | Prem | Bath | 26-31 |
| Loss | 21st March 2026 | Prem | Exeter Chiefs | 26-14 |
Sale have been struggling, and their only win since the Six Nations break was against Harlequins in the Champions Cup. They had a difficult day at home against the Saracens in the last round, conceding 13 tries to mid-table Saracens at home. Sanderson will be looking for a bounce-back performance against Quins.
Harlequins vs Sale Sharks head-to-head record (last five matches):
| Date | Competition | Winner | Score |
| 4th April 2026 | Champions Cup | Sale Sharks | 17-26 |
| 26th December 2025 | Prem | Sale Sharks | 43-17 |
| 19th April 2025 | Prem | Sale Sharks | 29-43 |
| 22nd September 2024 | Prem | Sale Sharks | 12-11 |
| 21st April 2024 | Prem | Sale Sharks | 37-31 |
Sale have won the last five meetings, including the one just three weeks ago. They won that match by nine points, but had won by at least 14 in the previous two wins.
