Dragons centre Adam Hughes has been forced to retire from professional rugby with immediate effect due to a brain injury, the BBC report.
Hughes, 28, spent the majority of his career with the Dragons after making his debut in 2010 and had brief spells at Bristol and Exeter.
The centre returned to the Welsh side three years ago and has made 119 appearances for the region during his time with Newport, scoring 22 tries and 124 points in the process.
Hughes has not featured in a Dragons squad since facing Ulster in the Guinness PRO14 back in September.
Despite several attempts at getting Hughes back out on the field in the time he has been out injured, they have all have been unsuccessful.
The former Bristol and Exeter player also suffered a serious concussion injury during a pre-season match back in August 2016, and was ruled out for five months.
With concerns over head injuries in all sport now taking very seriously, Hughes is the third Dragons player in three seasons to retire after suffering head injuries.